Fibroblast growth factor 2 isoforms and cardiac hypertrophy
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چکیده
منابع مشابه
Fibroblast growth factor 2 isoforms and cardiac hypertrophy.
Fibroblast growth factor 2 (FGF-2), a multifunctional polypeptide that affects cell growth and differentiation and becomes upregulated by stress, is expressed as AUG-initiated 18 kDa FGF-2 or CUG-initiated 21-34 kDa (hi-FGF-2) isoforms. Animal models have provided strong evidence that FGF-2 is essential for the manifestation of overload- and angiotensin-induced cardiac hypertrophy. Nevertheless...
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ژورنال
عنوان ژورنال: Cardiovascular Research
سال: 2004
ISSN: 0008-6363
DOI: 10.1016/j.cardiores.2004.04.024